Volume 179, Issue 7, July.-22

Editor’s Note

1. Neuroscientific Advances Supporting New Treatments for Major Depression

Editorials

2. Digital Therapeutics to Enhance Cognition in Major Depression: How Can We Make the Cognitive Gains Translate Into Functional Improvements?

3. Understanding the Efficacy and Mechanism of Action of a Dextromethorphan-Bupropion Combination: Where Does It Fit in the NMDA Versus mu-Opioid Story?

4. Is Neuroplasticity Key to Treatment Response in Depression? Maybe So

5. The Amygdala and Depression: A Sober Reconsideration

Reviews and Overviews

6. Toward a Better Understanding of the Mechanisms and Pathophysiology of Anhedonia: Are We Ready for Translation?

Articles

7. Longitudinal Trajectory of the Link Between Ventral Striatum and Depression in Adolescence

8. Digital Intervention for Cognitive Deficits in Major Depression: A Randomized Controlled Trial to Assess Efficacy and Safety in Adults

9. Effect of AXS-05 (Dextromethorphan-Bupropion) in Major Depressive Disorder: A Randomized Double-Blind Controlled Trial

10. Predictive Value of Acute Neuroplastic Response to rTMS in Treatment Outcome in Depression: A Concurrent TMS-fMRI Trial

Priority Data Letter

11. No Association Between Amygdala Responses to Negative Faces and Depressive Symptoms: Cross-Sectional Data from 28,638 Individuals in the UK Biobank Cohort