February 2022Volume 175, Issue 2

ORIGINAL RESEARCH

1. Characteristics and Outcomes of Hospitalized Pregnant Women With Influenza, 2010 to 2019

- A Repeated Cross-Sectional Study

2. Associations of Serum Testosterone and Sex Hormone–Binding Globulin With Incident Cardiovascular Events in Middle-Aged to Older Men

3. Comparison of a Hemostatic Powder and Standard Treatment in the Control of Active Bleeding From Upper Nonvariceal Lesions

- A Multicenter, Noninferiority, Randomized Trial

4. Comparative Effectiveness of an Automated Text Messaging Service for Monitoring COVID-19 at Home

5. Thiamine Supplementation in Patients With Alcohol Use Disorder Presenting With Acute Critical Illness

- A Nationwide Retrospective Observational Study

6. Comparing Video-Based, Telehealth-Delivered Exercise and Weight Loss Programs With Online Education on Outcomes of Knee Osteoarthritis

- A Randomized Trial

7. Pregnancy Outcomes in Women With a Prior Cervical Intraepithelial Neoplasia Grade 3 Diagnosis

- A Nationwide Population-Based Cohort Study With Sibling Comparison Design

8. Firearm Purchasing During the COVID-19 Pandemic: Results From the 2021 National Firearms Survey

9. Neutralization of SARS-CoV-2 Variants in Transplant Recipients After Two and Three Doses of mRNA-1273 Vaccine

- Secondary Analysis of a Randomized Trial

10. Responses to a Neutralizing Monoclonal Antibody for Hospitalized Patients With COVID-19 According to Baseline Antibody and Antigen Levels

- A Randomized Controlled Trial

REVIEWS

11. Safety and Efficiency of Diagnostic Strategies for Ruling Out Pulmonary Embolism in Clinically Relevant Patient Subgroups

- A Systematic Review and Individual-Patient Data Meta-analysis

12. Video Teleconferencing for Disease Prevention, Diagnosis, and Treatment

- A Rapid Review

BEYOND THE GUIDELINES

13. When and How Would You Screen This Patient for Cervical Cancer?

- Grand Rounds Discussion From Beth Israel Deaconess Medical Center

SPECIAL ARTICLES

14. COVID-19: Challenging Clinical Questions

IDEAS AND OPINIONS

15. Rebooting Instrumental Activities of Daily Living for the 21st Century

16. COVID-19 Vaccine Boosters for All Adults: An Optimal U.S. Approach?

17. Treating Opioid Withdrawal in the Hospital: A Role for Short-Acting Opioids

EDITORIALS

18. Influenza-Related Morbidity in Pregnancy: A Call for Maternal Immunization

19. Testosterone and Cardiovascular Disease in Men

20. The Role of Hemostatic Powder in Endoscopic Hemostasis of Nonvariceal Upper Gastrointestinal Bleeding

21. Extending a Lifeline to Nonhospitalized Patients With COVID-19 Through Automated Text Messaging

22. What Contributes to Pregnancy Complications Among Women With Cervical Intraepithelial Neoplasia Grade 3?

23. Higher D-Dimer Thresholds for Excluding Pulmonary Embolism: No Lunch?

ON BEING A DOCTOR

24. Swan Song

LETTERS

25. Change in Per Capita Opioid Prescriptions Filled at Retail Pharmacies, 2008–2009 to 2017–2018

- Observation: Brief Research Reports

26. Long-Term Risk for Major Bleeding During Extended Oral Anticoagulant Therapy for First Unprovoked Venous Thromboembolism

- Comment

- Response

27. Adding a New Medication Versus Maximizing Dose to Intensify Hypertension Treatment in Older Adults

- Comment

- Response

AD LIBITUM

28. Morning Groove

29. The restaurant

30. Villanelle in Honor of American Hospitals

IN THE CLINIC

31. Acute Gastrointestinal Bleeding

ACP JOURNAL CLUB

32. In patients with stable CVD receiving statins, evolocumab reduced acute arterial events across all vascular territories

33. In mild acute diverticulitis, outpatient therapy without antibiotics was noninferior to antibiotics

34. In patients hospitalized with COVID-19, therapeutic- vs. prophylactic-dose heparin did not reduce a composite outcome at 28 d

35. In high-risk inpatients with COVID-19, therapeutic- vs. standard-dose heparin reduced thromboembolism or death at 30 d

36. In COVID-19, escalated- vs. prophylactic-dose anticoagulation does not reduce mortality and increases major bleeding

37. In patients hospitalized for COPD exacerbation, a PE diagnostic strategy + usual care did not improve outcomes

38. In suspected or provisionally diagnosed ACS, early CTCA did not reduce mortality or nonfatal MI at 1 y

39. In permanent AF with narrow QRS, AV junction ablation + CRT vs. rate-control drug therapy reduced mortality

40. In AF after TAVR, edoxaban was noninferior to VKAs for a composite of adverse events but increased major bleeding

41. In critically ill adults, IV fluid bolus infused at slower vs. faster rates did not differ for 90-d mortality

WEB EXCLUSIVES

42. Annals Graphic Medicine - Dr. Mom: Which Hospital Snack Are You?

43. Annals Graphic Medicine - A Box of Chocolates

44. Annals for Educators - February 2022

45. Annals for Hospitalists Inpatient Notes - Another Way That Hospitalists Can Fight COVID-19