March 2022, Vol 140, No. 3, Pages 222-288

Viewpoint

1. Pentosan and Macular Disease—A Causal Association?

3. The Basic and Clinical Science Course of the American Academy of OphthalmologyThe 50th Anniversary of a Unicorn Among Medical Textbooks

Original Investigation

4. A National Analysis of Ophthalmic Features and Mortality in Abusive Head Trauma

5. Serious Adverse Events of Oral and Topical Carbonic Anhydrase Inhibitors

6. Association of Pegcetacoplan With Progression of Incomplete Retinal Pigment Epithelium and Outer Retinal Atrophy in Age-Related Macular DegenerationA Post Hoc Analysis of the FILLY Randomized Clinical Trial

7. Progression of Age-Related Macular Degeneration Among Individuals Homozygous for Risk Alleles on Chromosome 1 (CFH-CFHR5) or Chromosome 10 (ARMS2/HTRA1) or Both

8. Associations Between Retinal Nerve Fiber Layer and Ganglion Cell Layer in Middle Age and Cognition From Childhood to Adulthood

9. Visual Acuity and Ophthalmic Outcomes 5 Years After Cataract Surgery Among Children Younger Than 13 Years

Invited Commentary

10. Complement Inhibition in Age-Related Macular Degeneration—Treat Early!

11. Not All Genes Are Created Equal in Age-Related Macular Degeneration

12. Challenges in Management of Pediatric Cataract

JAMA Ophthalmology Clinical Challenge

13. Macular Fluid in a Patient With a Reported History of Normal-Tension Glaucoma

14. Bilateral Hemorrhagic Optic Disc Edema in a Middle-aged Man

15. Decreased Vision and Eye Pain in a 55-Year-Old Man

Observation

16. Presumed Glial Sprouts as a Predictor of Preretinal Neovascularization in Retinal Vein Occlusion

17. Scleral Histopathologic Findings of Hurler-Scheie Syndrome With Refractory Glaucoma

Ophthalmic Images

18. Giant Conjunctival Carcinoma in an Adult Man

19. Retinopathy in an Older Adult Man With Waldenström Macroglobulinemia

20. Optic Nerve–Associated Astrocytic Hamartoma With Corresponding Visual Field Defect

21. Endothelial Cell Morphology Surrounding a Descemet Membrane Break

Comment & Response

22. Low-Dose Bevacizumab—But What About Long-term Results?

23. Low-Dose Bevacizumab—But What About Long-term Results?—In Reply

JAMA Ophthalmology Masthead

24. JAMA Ophthalmology